Much to the sadness of those who had been involved in the movements that he had led, Machen died in 1937 at the age of 55. Some commentators point out that Machen’s “constitution” was not always strong, and that he was constantly “burdened” with his responsibilities at the time.
Machen had decided to honour some speaking engagements he had in North Dakota in December, 1936, but developed pleurisy in the exceptionally cold weather there. After Christmas, he was hospitalized for pneumonia and died on January 1, 1937. He is buried in Greenmount Cemetery, Baltimore.