Lewis’s mother, Florence Augusta ‘Flora’ Hamilton Lewis died of cancer in 1908 when Lewis was nine. Later he attributed his atheism in part to this early loss.
In 1916, Amy established a Protestant religious order called the Sisters of the Common Life.
In 1912, Queen Mary recognised Amy's missionary work and helped to fund a hospital in Dohnavur.
The Dohnavur Fellowship added a home for boys, usually the babies of rescued temple prostitutes, in 1918